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Oral GLP1s are a highpriority class for metabolic disease (obesity, type 2 diabetes) and Hengruis move signals Chinas accelerating push to develop homegrown oral GLP1 therapies amid global competition and mixed results from some multinational programs
GLP-1 receptor agonism is the backbone of many successful anti-obesity and anti-diabetic medications
Abstract Glucagon-like peptide-1 (GLP-1) is a gut-derived hormone essential for maintaining glucose homeostasis through multiple physiological pathways: triggering insulin release, inhibiting glucagon secretion, delaying gastric emptying, enhancing feelings of fullness, and suppressing appetite
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