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mTOR is a key modulator of ageing and age-related disease
Additionally, beta-glucan has been shown to improve insulin sensitivity, reduce cholesterol, and promote a lasting feeling of fullness, which can support appetite control and metabolic health
The perspective concludes that GLP-1 therapies should complement not replace exercise, and that improving adherence is now the central challenge in translating exercises proven benefits into real-world impact
Nat Med (2018) 24:111320
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