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General symptoms such as persistent fatigue, dizziness (especially upon standing), excessive thirst, or decreased urine output may reflect dehydration and electrolyte depletion
Foods to avoid on weightloss medication: Common triggers High-fat and greasy foods High-fat foods slow digestion significantly when taking GLP-1 medication
How Tirzepatide and Retatrutide Work Differently Both Tirzepatide and Retatrutide belong to the incretin-based class of medications, but they differ in the number of hormone receptors they activate
No direct drug interactions occur, but L-carnitine may slightly lower blood sugar in sensitive individuals, potentially amplifying tirzepatide's glucose-lowering effect
Common adverse effects of GLP-1 medications include: Gastrointestinal symptoms (nausea, vomiting, diarrhoea, constipation) affecting up to 40% of users, usually transient Injection site reactions Potential risk of pancreatitis (rare but serious) Gallbladder problems including gallstones Thyroid effects patients should report any thyroid symptoms (neck lump, persistent hoarseness) NICE technology appraisals (TA875 for semaglutide and TA664 for liraglutide) recommend that these medications should only be prescribed as part of a comprehensive weight management programme including dietary advice, physical activity support, and behavioural interventions
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