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Other notable observations included two separate occurrences of spontaneous compartment syndrome, suspicion of nonaccidental injury due to significant bruising, and significant clinical variability regarding the debilitating effect of joint dislocations
Potential endpoints include: Proteasome activity Ubiquitinated protein abundance Protein-degradation rates Misfolded-protein markers Autophagy-associated measurements Stress-response proteins Protein aggregation Cell viability under controlled stress Changes in proteostasis markers do not independently establish cellular rejuvenation or anti-aging effects
Presented for research literature review only Jadeja RN et al
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