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Third, individual variation is substantial: patients with severe insulin resistance or significant mitochondrial dysfunction may respond at lower doses than metabolically healthy athletes

3 The American Academy of Pediatrics recommends considering pharmacotherapy for adolescents with obesity, but the introduction of potent medications (eg, GLP-1 receptor agonists) presents a host of complex psychosocial and financial questions that extend beyond clinical efficacy

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Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension