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The US National Food and Nutrition Board (FNB) of the National Academies (formerly the National Academy of Sciences) carried out studies in 1989 to investigate the functions of carnitine and came to the conclusion that it was not an essential nutrient acts
The side effects guide discusses GHK-Cu reactions in more detail
A 2007 double-blind, multicenter trial (n=102) showed ALC 1,500 mg/day significantly improved tender point count, total myalgic score, depression, and musculoskeletal pain compared to placebo.[9] A 2015 RCT found ALC 1,500 mg/day comparable to duloxetine 60 mg/day for pain and depression.[8] Most notably, a 2023 RCT demonstrated that adding PEA 1,200 mg/day + ALC 2,000 mg/day to ongoing duloxetine + pregabalin therapy produced significantly greater improvements in Widespread Pain Index, FIQR, and FASmod scores.[7] Role in Treatment: ALC can be used as monotherapy or adjunctive therapy in fibromyalgia
Do not take more than the recommended dose