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Controlled human safety, pharmacokinetic, and efficacy studies have not been published in peer-reviewed clinical literature

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however, unlike nicotinic acid, niacinamide does not usually cause the intense flushing reaction (redness/itching) of the skin

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2 Its recommended that you consume 50mg per kg of body mass of leucine daily, which can be achieved through your diet (chicken, tuna, and tofu are good options) or a supplement (whey protein has the highest leucine content)