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Glucose-6-phosphate dehydrogenase is found in all cells and is responsible for the first reaction of the pentose phosphate pathway in which glucose-6-phosphate is oxidized to 6-phosphogluconolactone with concomitant production of NADPH
GLP-1 receptors are expressed throughout the central nervous system, including in the hypothalamus, which governs hunger and energy balance, and in the mesolimbic dopamine pathway the brain's reward circuit
Nasser Nasseri, M.D
The EXSCEL trial with exenatide showed similar glycemic and weight benefits, accompanied by trends toward better microvascular outcomes [30]
It works by mimicking natural hormones found in the body (GLP-1 and GIP) that help regulate blood sugar and cause you to feel full
