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Research Applications DSIP research spans sleep architecture modulation, HPA axis regulation (ACTH and cortisol), neuroprotection, antioxidant activity, and pain modulation

There is no clinical trial data specifically studying this approach, but some prescribers report anecdotally that patients maintain better long-term responses with periodic dose reductions

The histological assessment used to investigate the healing parameters of the mice included edema, formation of blood vessels, retained follicles, formation of reticulin and collagen, number of inflammatory cells, and the number of subjects experiencing complete re-epithelialization

Reference: Sikiric P, Seiwerth S, Grabarevic Z, et al

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