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Furthermore, the year of publication and dosage were found not to be a source of heterogeneity (Table 4)
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For Wegovy (higher-dose semaglutide for weight management), rates were higher, affecting approximately 29.3% of patients across the STEP clinical trials, with most cases occurring during dose escalation phases
Patients experiencing persistent changes should consult their healthcare providers, who can: Monitor hormone levels Adjust medication dosage if needed Recommend appropriate management strategies The relationship between Ozempic or Wegovy and hormonal function continues to be studied, with research showing both direct and indirect effects on the endocrine system
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