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Under normal conditions, only a minority of scalp follicles are in telogen at one time, so shedding stays spread out

When melanocytes are hyperactivated by specific triggers UV radiation, post-inflammatory signals from acne or injury, hormonal changes (especially estrogen and progesterone in melasma), or genetic predisposition they produce excess melanin that accumulates in patches, creating dark spots, uneven tone and visible discolouration

Wegovy brought in USD 7.1 billion in revenue globally, whereas Ozempic sales stood at approximately USD 15.4 billion

But none of this happens fast

The thesis-confirming move is to notice what retatrutide does to the conversation