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Using genetically engineered mouse models and patient-derived xenografts (PDXs), Chen et al

Why it's not available: Never achieved FDA approval or met compounding criteria

Aged garlic extract enhances heme oxygenase-1 and glutamate-cysteine ligase modifier subunit expression via the nuclear factor erythroid 2-related factor 2-antioxidant response element signaling pathway in human endothelial cells

This activation results in several beneficial effects mimicking the hormone's natural functions

This matters for anyone exploring peptides for weight loss because the hormonal environment around visceral fat is fundamentally different from subcutaneous fat