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Reactive oxygen species (ROS), generated by nicotinamide-adenine-dinucleotide-phosphate (NADPH) oxidases, mitochondrial dysfunction, and uncoupled eNOS, deplete NO and oxidize cellular lipids and proteins (40)
J Clin Endocrinol Metab (2020) 105(8):e27106
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Anti-inflammatory peptides act on several pathways: modulating pro-inflammatory cytokines, inhibiting the NF-kB signaling pathway, shifting macrophages toward a healing state, and enhancing antioxidant defenses
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