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The weight loss in the SELECT trial wasnt especially large on average, each participant lost around 8 to 9 percent of their body weight

STEP 4 is the important counterpoint: weight came back when treatment stopped, so this is a long-term treatment rather than a short course, and whether it is right for you is a decision for the prescribing doctor

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There are other FDA-approved oral weight-loss medications available through a prescription, like phentermine, Contrave , and Qsymia

Cocaine and amphetamines (stimulants) All animal studies retrieved for stimulants misuse involved exendin-4 among GLP-1RAs and highlighted a reduction of cocaine and amphetamines intake and end effects (for example, increased locomotor activity) via modulation of dopaminergic transmission in areas including the nucleus accumbens and the ventral tegmental area 91,92,93,94,96,97,98,99,100,101,102,103,105 , as well as modulation of inflammatory mechanisms 104