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Additionally, Epithalon is associated with antioxidant activity, helping reduce oxidative stress and protect cells from damage

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Long-term use of metformin, proton pump inhibitors or H2 blockers , which can reduce B12 absorption over years

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This matters most in longitudinal or multi-cohort research, where a vial reconstituted three weeks ago and a freshly prepared vial from the same batch may behave differently in downstream results a discrepancy that is trivial to explain with a log and easy to misattribute to biological variance without one