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Interestingly, IR-deficient chondrocytes had increased IGF-1R levels and were more responsive to IGF-1 consistent with the notion that IGF-1/IGF-1R may compensate, at least in part, for loss of IR signaling

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Side effects are similar, but retatrutide saw higher rates of dysesthesia: Most side effectsnausea, vomiting, diarrhealook familiar and are common to this class of medication

doi: 10.1530/JOE-14-0615 176 TianPOriordanKJLeeY-KWangGZhaoJZhangHet al