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This improvement in half-life is expected to prolong their therapeutic action, reduce dosing frequency, and enhance patient adherence
Eligible randomized controlled trials included at least 500 participants with type 2 diabetes, compared GLP-1 receptor agonists to placebo over at least 12 months, and reported clinical kidney or cardiovascular outcomes
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Pain 153 , 18151823 (2012)
doi:10.1371/journal.pone.0078315 36
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