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Expected 12-week outcome: approximately 1-2 kg additional fat loss, primarily from subcutaneous stores in the lower abdomen and flanks
The FDA-approved prescribing information for tirzepatide explicitly states that "there are no data on the presence of tirzepatide in human milk, the effects on the breastfed infant, or the effects on milk production." This absence of data reflects the exclusion of pregnant and breastfeeding individuals from clinical trials, a common practice that creates knowledge gaps for this population
Originally, the GLP-1 agonists were created to treat type 2 diabetes
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In the liver, it diminishes glucose production by blocking gluconeogenic enzymes, which are essential proteins in glucose synthesis (Ahrn 2015
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