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To further confirm this potential shift in the conformational equilibrium, we collected a second cryo-EM dataset for Cagri-CTR ( N = 2) from a separate protein purification
[3] The doses used in these tendon studies typically ranged from 10 to 200 micrograms per kilogram of body weight, administered once daily, which when extrapolated to a 75-kilogram human would suggest a working range of approximately 200 to 500 micrograms per day
(1) Classical GPx (GPx1) is reported to be expressed in red blood cells and liver, lung, and kidney tissues and is located in the cytosol, nucleus, and mitochondria
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