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third, SCFAs modulate the secretion of GLP-1 and PYY, indirectly influencing HPG axis function, with their dysregulation linked to hyperandrogenism and ovulatory dysfunction

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however, this is FDA staff's proposed position going into the meeting, not a final action, and the committee's discussion, any vote, and FDA's ultimate decision are still pending, so the outcome of the review is not yet known

Plaza-Diaz J, Gomez-Fernandez A, Chueca N, Torre-Aguilar MJ, Gil A, Perez-Navero JL, et al