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monotherapy doses in the Phase 2 dose-finding trial spanned 0.3 mg to 4.5 mg, with 2.4 mg used in the CagriSema combination
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The derivatives were resolved and detected using liquid chromatography/electron spray ionization/tandem mass spectrometry in multi-reaction monitoring mode
Early treatment helps prevent symptoms from worsening
But more noticeable or stubborn pigmentation typically needs active ingredients like Vitamin C, Niacinamide, or AHAs
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