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Design of a novel long-acting dual GLP-1/GIP receptor agonist
Nature 580 , 511516 (2020)
Crucially, the researchers noted that the S-A-GSH molecule was rapidly deacetylated once inside the body, proving that the acetyl shield successfully protected the compound through the digestive tract and then efficiently released the intact, active glutathione directly into the intracellular environment where it is needed to combat oxidative stress
The medication is a protein-based peptide that degrades when exposed to heat, light, or contamination
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