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The reported HOMA index was calculated according to the method of Matthews et al [15], while insulin secretion index was derived from the method of Phillips et al [16]

FDA-approved for chronic weight management, Zepbound helps reduce appetite, slow stomach emptying, and improve blood sugar regulation

Stabilizing hormones during this transitional period can help maintain consistent GLP-1 responses

In fact, obesity treatment guidelines emphasize that GLP-1 medication should be combined with a high-protein diet, increased physical activity, and behavioral interventions (self-tracking, therapy, group support, dietary education, etc.)