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Proc Natl Acad Sci USA 87: 16201624

This article examines GHK-Cu within laboratory, biochemical, cellular, analytical, and controlled preclinical research contexts

In contrast, when tissue folate or cobalamin stores are intact (Silberberg et al, 1997) or in the case of an alteration of the transsulfuration pathway dependent on vitamin B 6 deficiency or on heterozygosity for a CBS defect (Bostom et al, 1995a), an excessive methionine supply might lead to an important elevation of plasma homocysteine

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