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"Semaglutide and Cardiovascular Outcomes by Baseline and Changes in Adiposity Measurements: A Prespecified Analysis of the SELECT Trial"

A meta-analysis of 15 RCTs contrasting the combination of GLP-1RA and basal insulin with other antidiabetic agents showed 0.44% and 3.22 kg greater decrease in HbA1c and body weight, respectively, by combining GLP-1RA and basal insulin without increasing hypoglycemic risk (21)

In practice, however: without a serious and progressive training programme, peptides alone will not build muscle

As you get older, your body makes less collagen and breaks it down faster, causing your skin to wrinkle and sag and your muscles, bones, and tendons to shrink, stiffen, and get weaker

Frontiers in Nuclear Medicine