Drugs like Ozempic and Wegovy have already been found to cause unpleasant gastrointestinal side effects, and rapid weight loss can produce sagging skin, which some have started calling Ozempic face. Additionally, patients are likely to need to continue using the medications long-term to maintain their weight
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Human colonic microbiota associated with diet, obesity and weight loss
For researchers starting at 2.5mg weekly and escalating to 5mg, a 10mg vial provides exactly four weeks at starting dose then another four weeks at increased dose when you account for the step-up timeline
As for topical application, the studies are also promising