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Pioglitazone carries an FDA warning about bladder cancer risk based on epidemiological signals, though absolute risk increases appear small
PI/Ca : Experimental studies have shown that increased cAMP and PKA activation inhibits methacholine- and histamine-induced phosphoinositide (PI) hydrolysis and its effect to cause Ca2+ mobilization (Hoiting et al, 1996
The Mental Load of Rapid Change Another thing to consider: rapid weight loss can be emotionally destabilizing
doi: 10.1194/jlr.M800520-JLR200 61
How to apply Larsen score in evaluating radiographs of rheumatoid arthritis in long-term studies
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