vulgatus showed that Guinea pigs that were immunized with dead bacteria, then fed both PGN and viable bacteria for 30 days sustained more inflammation in the GI tract and suffered more severe lesions in the caecum and large intestine than the non-immunized Guinea pigs, and that the severity of the disease was influenced by the duration of the immunization (Onderdonk, Cisneros and Bronson 1983 Onderdonk, A
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