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Excitotoxicity : Excessive glutamate release resulting in sodium and calcium influx, which impairs neuronal viability
Copper peptides, and specifically GHK-Cu, are one of the more interesting compounds in that marketplace because they are not new, they are not synthetic, and they have a body of research stretching back over fifty years
However, tesofensine did cause increases in heart rate and blood pressure, especially at higher doses
An ideal scenario would involve the use of pro-senescence drugs with high efficacy in inducing senescence in a substantial proportion of cancer cells [60]
Holscher HD
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