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10.1016/s0008-6363(02)00809-x 7 BaggioL
Brown, B., Alphs, L., Turkoz, I
Metabolic Effects of DPP-4 Related to Its Enzymatic Activity Despite DPP-4 having a relatively restricted substrate preference (Figure 1), a large number of peptides, proteins, and chemokines still fulfill the criteria and could be predicted to be suitable substrates, and indeed, many have been shown to be cleaved by DPP-4 in pharmacological kinetic, in vitro or animal studies, often using high substrate concentrations (1, 4, 3638)
Diabetologia 61:21082117 Ganbaatar B, Fukuda D, Shinohara M, Yagi S, Kusunose K, Yamada H, Soeki T, Hirata KI, Sata M (2020) Empagliflozin ameliorates endothelial dysfunction and suppresses atherogenesis in diabetic apolipoprotein E-deficient mice
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