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Abdellatif A, Bahria K, Slama N, Oukrif D, Shalaby A, Birkmayer G, et al

The role of the gut as a mediator is unequivocally demonstrated in models of chronic apical periodontitis (CAP), where P.g -induced CAP alters gut microbiota (increasing Lachnospiraceae , Ruminococcaceae ) and increases TMAO, thereby exacerbating aortic plaque formation

This mirrors the escalation approach used with semaglutide, which makes sense given that Novo Nordisk designed both compounds

Research indicates that the co-existence of PCOS and MASLD increases the likelihood of developing type 2 diabetes, cardiovascular disease, and chronic kidney disease, which are more serious and difficult to manage than MASLD alone (Shahbaz et al., 2022)

This gene modulation isnt limited to muscles and tendons