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Based on clinical trial data, starting doses are usually between 1 mg and 4 mg, administered once a week via subQ

The pricing structure itself is dictated by federal rules, noted Broussenko, underscoring how generic drug prices in Canada are indexed as a percentage of the brand-name price, creating a price floor that applies across the board

A 2024 phase 2 trial published in Nature Medicine enrolled 98 adults with confirmed obesity and fatty liver, treating them with retatrutide once weekly for 48 weeks