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Conversely, patients who carry variants in hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, rs72613567) and mitochondrial amidoxime-reducing component 1 (MARC1, rs2642438) are more protected than the general population (48, 49)
GLP-1 drugs may help with appetite and weight reduction, but they may also create clinically meaningful nutritional side effects, especially in patients with poor baseline diet quality, prolonged use, gastrointestinal side effects, or rapid weight loss
Furthermore, there is a growing trend towards combining multiple PRR agonists to enhance their targeting of APCs
10.1097/CMR.0000000000000181 255 ShinA