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They tell the body to upregulate processes it already knows how to do, such as repair, regeneration, or metabolic regulation, explains Amanda Kahn, MD, a board-certified internist in New York City

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In innate immunity, succinate may be one of the major signaling molecules (72), identifying metabolic activity as a key determinant of regulating the intensity of inflammation

It is one of the most extensively studied compounds in angiogenesis and wound-healing research, with models focusing on tendon-to-bone healing, new blood-vessel formation, and gastrointestinal tissue repair

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