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After the microneedle is inserted into the psoriatic skin, the needle tip separates from the base, and MTX is rapidly released from the swollen gel pores, promptly inhibiting keratinocyte proliferation, while EGCG breaks the bond in response to the high ROS environment in the skin and releases in an intelligent and controlled manner, effectively inhibiting the NF-B inflammatory pathway for a long time (Zhao Y

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Pre-treatment of rats with 120 g/kg DSIP 20 minutes prior to subjection to hypoxia completely inhibited these hypoxia-induced reductions in mitochondrial respiratory activity

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Of the many nutrients found in MedDiet, omega-3 polyunsaturated fatty acid (PUFAs) is perhaps the most widely studied, exerting the greatest benefits as an adjuvant for mental disorders [287]