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some may respond within 15 minutes at higher doses [9] These medications work by enhancing nitric oxide-mediated relaxation of penile smooth muscle, facilitating increased blood flow during sexual stimulation

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Research protocols show that after single-dose administration, more than half of senescent cells disappear while healthy cells remain intact, providing researchers with quantitative measures of senolytic efficacy

TABLE 1 Small molecules in hepatic differentiation and reprogramming