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Aligned with a clinically detectable change in the taste recognition threshold, says Jane, we demonstrated that semaglutide treatment affected gene transcription in the tongue

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N Engl J Med 377:644657 Wiviott SD, Raz I, Bonaca MP, Mosenzon O, Kato ET, Cahn A, Silverman MG, Zelniker TA, Kuder JF, Murphy SA, Bhatt DL, Leiter LA, McGuire DK, Wilding JPH, Ruff CT, Gause-Nilsson IAM, Fredriksson M, Johansson PA, Langkilde AM, Sabatine MS (2019) Dapagliflozin and cardiovascular outcomes in type 2 diabetes

They are suitable for occasional use when more rapid relief is needed but are not typically recommended as sole maintenance therapy

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