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Brain modulation by electric currents in fibromyalgia: a structured review on non-invasive approach with transcranial electrical stimulation

Worth a read for anyone following obesity care and real-world evidence: To view or add a comment, sign in A diagnostic paradox buried in the Lancet obesity framework: Patient A: HbA1c 6.1% + dyslipidemia meets definition of "clinical obesity" Patient B: HbA1c 6.8% (diagnosed T2DM) + normal lipids may not qualify as "clinical obesity" T2DM was excluded from the organ-dysfunction criteria despite: ~90% of T2DM patients being overweight or obese Strong mechanistic links to visceral & ectopic fat ~50% diabetes remission rate with intensive weight loss at 1 year This inconsistency may create real coverage and access problems

Weight loss from GLP-1 therapy includes some loss of lean body mass, with studies suggesting that approximately Short-term clinical trials have generally shown preserved muscle strength despite reductions in lean mass, and some studies suggest these medications may improve muscle quality by reducing fat infiltration within muscle tissue

This sits right in the middle of the escalation schedule, prescribed during weeks nine through twelve for patients following the standard protocol

The patients who maintain results best are those who used the treatment period to build strong protein-forward nutrition habits, preserve muscle mass through resistance exercise, and work with a physician on a planned tapering and maintenance strategy