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You may remember that Avandia was actually pulled from the market because of increased heart failure risk, and that this led to a revolution in diabetes care prioritizing cardiovascular safety before diabetes drugs could be FDA approved
J Med Invest (2018) 65(1.2):917
TD is also known to induce gastric ulceration (85)
Therefore, given the pleiotropic functions of -KG, we aimed to explore whether and how -KG potentially regulates energy sensing and metabolic adaptation of cancer cells to energy stress
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