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Incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual glucose-dependent insulinotropicGLP-1RAs, have evolved from metabolic therapies to agents with either proven or potential protective effects on the kidney and heart
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Narasimhan, M
In a post-hoc analysis of AWARD-11, the effect of dulaglutide treatment was associated with consistent safety and efficacy patterns regardless of their renal function status at baseline, with no more gastrointestinal adverse effects nor hypoglycemic events in those subjects with lower renal function [95]
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