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Compounded GLP-1s are not FDA approved and does not undergo the same rigorous efficacy and safety checks as do FDA-approved medications

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SEP-479 oral small-molecule agonist of the parathyroid hormone 1 receptor (PTH1R) aimed at treating hypoparathyroidism Recent Highlights: In May 2025, Septerna signed an exclusive global collaboration with Novo Nordisk worth up to $2.2B to co-develop oral small molecule GLP-1, GIP, and glucagon receptor agonists

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Both versions have selective influence on blood glucose regulation but may have minor effects on weight loss as well with fewer side effects compared to other antidiabetic medications that can cause hypoglycemia or gastrointestinal issues

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