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NRXN1 knock-out mice models show that -neurexins are crucial for maintaining post-synaptic NMDA-receptor function, regulating synaptic transmission, and organizing the pre-synaptic terminals by coupling Ca 2+ channels on the pre-synaptic surface [50,51,52], accompanied by behavioral abnormalities that resemble the core symptoms of ASD [53]
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8 Therapeutical approaches for long COVID-19 Prospective interventions studies on L-C19 include rehabilitation programs (on-site or online) for cognitive disorders, targeted drug therapies (specific drugs or microbiota modulating drugs), metabolic modulators, immunomodulatory therapies, antifibrotic and anticoagulation therapies (232, 233)
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