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Eur Heart J Cardiovasc Pharmacother 2:244255 Verma S, McMurray JJ (2018) SGLT2 inhibitors and mechanisms of cardiovascular benefit: a state-of-the-art review
The most frequently reported side effects in Phase 2 trials are gastrointestinal: nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
Urinary sodium, potassium, and chloride were quantified by DRI-CHEM 800 (Fujifilm, Tokyo, Japan)
This molecule works by slowing gastric emptying and signaling the brains satiety centers to reduce food cravings
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