what is the mechanism of action of tirzepatide

what is the mechanism of action of tirzepatide Tirzepatide: A Double Approach to Diabetes and Weight Loss Retatrutide vs Tirzepatide vs Semaglutide:

Name: what is the mechanism of action of tirzepatide Tirzepatide: A Double Approach to Diabetes and Weight Loss Retatrutide vs Tirzepatide vs Semaglutide:
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The protective effects of GLP-1 are dependent on downstream inhibition of Rho through a cAMP/PKA-mediated pathway [58]

Figure 4C showed appendectomy did not increase risk of CRC(OR:1.005, 95%CI:0.992-1.018, P=0.459)

One patient (patient #11) had an increase of triglyceride levels while on tirzepatide and did not have any obvious clinical explanation for the increase