Underlying Health Conditions: Conditions like pernicious anemia, Crohns disease, or celiac disease can affect B12 absorption and necessitate ongoing treatment
Experiments conducted on isolated bovine chondrocytes also revealed an apparent upregulation in the production of proteoglycans and collagen in these laboratory settings, fundamental components of the extracellular matrix considered essential for cartilage integrity
Deficiencies can occur with medical conditions such as atrophic gastritis (which causes thinning of the stomach lining), pernicious anaemia, Crohns disease, celiac disease, lupus, or other immune system disorders and certain medications
Studies indicate that individuals with lower B12 levels are more likely to be obese[2], even after accounting for factors like diet, lifestyle and medication use
For people with digestion and nutrient absorption difficulties, getting the full benefit from supplements you buy at the store can be difficult especially if they come in much lower doses than you need for your health