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Research Evidence Comparison# Survodutide Research# Survodutide's clinical evidence is growing but remains primarily Phase 2: Phase 2 obesity trial : Randomized, dose-ranging study demonstrated up to 18.7% body weight loss at 46 weeks with the 4.8 mg dose, with dose-dependent efficacy across all arms Phase 2 MASH trial : Demonstrated significant reductions in liver fat content measured by MRI-PDFF, with histological improvement in MASH activity scores including inflammation and ballooning

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Step 3 Injection Training and Self-Administration: Once-weekly subcutaneous injection using a pre-filled pen device, rotating injection sites between abdomen, thigh, and upper arm