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42 The FIGHT trial, which enrolled patients hospitalised for acute decompensated HFrEF, showed no improvement with liraglutide on the primary composite endpoint of death, HF rehospitalisation or change in N-terminal pro B-type natriuretic peptide levels
It reduces glucose production by the liver and improves insulin sensitivity, and may raise your own GLP-1 levels slightly as a downstream effect, but it is not a GLP-1 receptor agonist
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Can be adjusted based on individual needs
Preclinical studies have already demonstrated the beneficial effects of GLP-1 on myocardium and vascular endothelium, and many clinical studies evaluating changes in surrogate markers of CVD have suggested potential benefits from the use of GLP-1 RAs
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