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This is due, in part, to their specialized function of producing melanin (which generates by-products such as O2 and H2O2) and inflammation due to excessive photo exposure.47,48 In the hair follicle, the outer sheath melanocytes are responsible for intense melanin synthesis
S2CID 1070555
It has been shown by various methods (subcellular fractionation, electron and fluorescence microscopy) that in the absence of insulin in these tissues, most (approximately 95%) of GLUT4 is located intracellularly
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
Adult hippocampal neurogenesis is regulated by the microbiome
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