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The adverse effects of NO on the respiratory tract can be attributed mostly to the production of ONOO and other RNS (NO 2 ) (93)
Similarly, oral glutathione supplements have historically been considered poorly bioavailable, though newer formulations (liposomal, sublingual, S-acetyl) aim to improve this [1][12]
Emphasis is placed on clinical screening, controlled titration, and ongoing monitoring to align outcomes with safety parameters
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