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12,399 These tools have revolutionized our ability to dissect the biological features of malignant tumor cells, uncover intratumoral heterogeneity and its dynamic evolution, elucidate tumor-immune cell interactions, and uncover mechanisms of drug resistance and relapse, paving the way for personalized treatment strategies to improve patient outcomes (Fig
D., Jenkins, R
187 A study also shows that purpurin and its analog, R162, acting as mixed model inhibitors of GDH1, inhibit GDH1 activity, elevate ROS levels and thus attenuate cancer cell proliferation
Disability and health journal, 4(2), 59-67
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